FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\nanosΔEX
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General Information
Symbol
Dmel\nanosΔEX
Species
D. melanogaster
Name
FlyBase ID
FBal0056429
Feature type
allele
Associated gene
Dmel\nanos
Associated Insertion(s)
Carried in Construct
P{nanos(ΔEX)}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Dahanukar and Wharton, 1996)
Progenitor genotype
nanosTCE.bcdUTR
(Dahanukar and Wharton, 1996)
Carried in construct
P{nanos(ΔEX)}
Cytology
Description

Deletion of nucleotides 618-844 of the nos 3'UTR.

(Rouget et al., 2010)

Construct: Deletion of the EarI-XhoI fragment from the nos 3' UTR.

(Dahanukar and Wharton, 1996)
Allele components
Component
Use(s)
Encoded product / tool
nanos
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      35% of embryos derived from nosΔEX females do not hatch and 86% of those that do hatch show head skeleton defects.

      (Rouget et al., 2010)

      Complements the embryonic segmentation defects of nos-. Cannot restore abdominal segmentation to osk- and vas- embryos.

      (Dahanukar and Wharton, 1996)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      nanosΔEX
      nosΔEX
      Name Synonyms
      Secondary FlyBase IDs
        References (2)