FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\mamsAX8
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General Information
Symbol
Dmel\mamsAX8
Species
D. melanogaster
Name
FlyBase ID
FBal0056509
Feature type
allele
Associated gene
Dmel\mam
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

gain of function allele

Mutagen
Nature of the Allele
Allele class

gain of function allele

(Verheyen et al., 1996)
Mutagen
ethyl methanesulfonate
(Verheyen et al., 1996)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      mamsAX8/mam[+] is an enhancer of visible phenotype of armS44Y.GMR

      (Kankel et al., 2007)

      mamsAX8/mam[+] is an enhancer of visible phenotype of armS56F.GMR

      (Kankel et al., 2007)
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      mamsAX8/mam[+] is an enhancer of eye phenotype of armS44Y.GMR

      (Kankel et al., 2007)

      mamsAX8/mam[+] is an enhancer of eye phenotype of armS56F.GMR

      (Kankel et al., 2007)
      Suppressor of
      Statement
      Reference

      mamsAX8 is a suppressor of phenotype of Nact.sev

      (Verheyen et al., 1996)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      mamsAX8/+ enhances the armS44Y.GMR and armS56F.GMR eye phenotypes.

      (Kankel et al., 2007)

      Second site dominant suppressor of Nact.sev that reduces the external roughness of the eye, in addition to causing the overall eye shape to become both rounder and larger, and less refractile. Fails to enhance the Su(H)T4 wing phenotype.

      (Verheyen et al., 1996)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      mamsAX8
      (Kankel et al., 2007)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)