FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\htlLH14
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General Information
Symbol
Dmel\htlLH14
Species
D. melanogaster
Name
FlyBase ID
FBal0057260
Feature type
allele
Associated gene
Dmel\htl
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
Delta2-3 transposase
(Beiman et al., 1996)
Progenitor genotype
P{PZ}sr03999
(Beiman et al., 1996)
Cytology
Description

Both htl exons are deleted.

(Beiman et al., 1996)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      htlΔ30/htlLH14 transheterozygous embryos show defects in the migration and organisation of the mesodermal cells. Homozygous embryos exhibit irregular patches of visceral mesoderm that fail to fuse. htlΔ30/htlLH14 transheterozygous embryos have only small patches of visceral mesoderm. Homozygous embryos have no heart. htlΔ30/htlLH14 transheterozygous embryos have few muscles that show irregular organisation and attachment.

      (Beiman et al., 1996)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Original P{PZ} insertion in sr is retained.

      (Beiman et al., 1996)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      htlLH14
      Name Synonyms
      Secondary FlyBase IDs
        References (1)