FB2026_02 , released June 18, 2026
Allele: Dmel\en::ftzEFE.F175E.hs
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General Information
Symbol
Dmel\en::ftzEFE.F175E.hs
Species
D. melanogaster
Name
FlyBase ID
FBal0057491
Feature type
allele
Associated gene
en::ftz
Associated Insertion(s)
Carried in Construct
P{hs-EFEΔF->E}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Smith and Jaynes, 1996)
Progenitor genotype
en::ftzEFE.hs
(Smith and Jaynes, 1996)
Carried in construct
P{hs-EFEΔF->E}
Cytology
Description

Construct: Amino acid replacement: F175E.

(Smith and Jaynes, 1996)
Allele components
Component
Use(s)
Regulatory region(s)
Hsp70
Encoded product / tool
en::ftz
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      After a 15 minute heat shock few embryos fail to hatch. Embryonic cuticle shows no ftz-dependent defects. Co-expression with en::ftzEFE.hs reduces the number of en::ftzEFE.hs embryos with pattern defects.

      (Tolkunova et al., 1998)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Carried in plasmid "pEFEΔF->E", expressed in S2 cells and competition for ftz binding sites on a Ecol\CAT reporter plasmid is studied.

      (Smith and Jaynes, 1996)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      en::ftzEFE.F175E.hs
      Name Synonyms
      Secondary FlyBase IDs
        References (2)