FlyBase Allele Report: Dmel\S[UAS.cGa]

General Information

Symbol

Dmel\S^UAS.cGa

Species

D. melanogaster

Name

Saccharomyces cerevisiae UAS construct a of Golembo

FlyBase ID

FBal0058291

Feature type

allele

Associated gene

Dmel\S

Associated Insertion(s)

Carried in Construct

P{UAS-Star}

Also Known As

UAS-Star, UAS-S

Key Links

Transgenic product class

cDNA

(Golembo et al., 1996)

wild_type

(Golembo et al., 1996)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

cDNA

(Golembo et al., 1996)

wild_type

(Golembo et al., 1996)

Mutagen

in vitro construct

(Golembo et al., 1996)

Progenitor genotype

Carried in construct

P{UAS-Star}

Cytology

Description

UASt regulatory sequences drive expression of a 3.3kb EcoRI cDNA fragment containing the entire S coding sequence.

(Golembo et al., 1996)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible, with Scer\GAL4^GMR.PF

(Hsiung et al., 2001)

Phenotype Manifest In

eye, with Scer\GAL4^GMR.PF

(Hsiung et al., 2001)

midline glial cell, with Scer\GAL4^elav.PLu

(Bergmann et al., 2002)

Detailed Description

Statement

Reference

S^Scer\UAS.cGa; Scer\GAL4^elav.PLu embryos have increased numbers of midline glial cells.

(Bergmann et al., 2002)

S^Scer\UAS.cGa when driven by Scer\GAL4^GMR.PF produces a moderate rough eye phenotype.

(Hsiung et al., 2001)

Expression of S^Scer\UAS.cGa under the control of Scer\GAL4^dpp.blk1 does not induce ectopic furrow formation in the eye disc.

(Kumar and Moses, 2001)

Expression of S^Scer\UAS.cGa using Scer\GAL4^ap-md544 does not produce a wing phenotype.

(Pickup and Banerjee, 1999)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

S^UAS.cGa, Scer\GAL4^GMR.PF has visible phenotype, enhanceable by spi^UAS.cSa, Scer\GAL4^GMR.PF

(Hsiung et al., 2001)

Enhancer of

Statement

Reference

S^UAS.cGa, Scer\GAL4^Bx-MS1096 is an enhancer of visible phenotype of Scer\GAL4^Bx-MS1096, Tcas\stet^UAS.GFP

(Rousso et al., 2010)

S^UAS.cGa, Scer\GAL4^Bx-MS1096 is an enhancer of visible phenotype of Scer\GAL4^Bx-MS1096, Tcas\stet^{UAS.GFP,Tag:ER(KDEL)}

(Rousso et al., 2010)

Other

Statement

Reference

S^UAS.cGa, Scer\GAL4^ap-md544, spi^UAS.cSa has visible phenotype

(Pickup and Banerjee, 1999)

S^UAS.cGa, Scer\GAL4^ap-md544, spi^UAS.cSa has increased occurrence of cell division | larval stage phenotype

(Pickup and Banerjee, 1999)

Phenotype Manifest In

Enhanced by

Statement

Reference

S^UAS.cGa, Scer\GAL4^Bx-MS1096 has wing vein phenotype, enhanceable by rho-4^UAS.cUa, Scer\GAL4^Bx-MS1096

(Urban et al., 2002)

S^UAS.cGa, Scer\GAL4^Bx-MS1096 has wing phenotype, enhanceable by rho-4^UAS.cUa, Scer\GAL4^Bx-MS1096

(Urban et al., 2002)

S^UAS.cGa, Scer\GAL4^GMR.PF has eye phenotype, enhanceable by spi^UAS.cSa, Scer\GAL4^GMR.PF

(Hsiung et al., 2001)

Enhancer of

Statement

Reference

S^UAS.cGa, Scer\GAL4^Bx-MS1096 is an enhancer of wing vein | ectopic phenotype of Scer\GAL4^Bx-MS1096, Tcas\stet^UAS.GFP

(Rousso et al., 2010)

S^UAS.cGa, Scer\GAL4^Bx-MS1096 is an enhancer of wing vein | ectopic phenotype of Scer\GAL4^Bx-MS1096, Tcas\stet^{UAS.GFP,Tag:ER(KDEL)}

(Rousso et al., 2010)

S^UAS.cGa, Scer\GAL4^Bx-MS1096 is an enhancer of wing vein phenotype of Scer\GAL4^Bx-MS1096, rho-4^UAS.cUa

(Urban et al., 2002)

S^UAS.cGa, Scer\GAL4^Bx-MS1096 is an enhancer of wing phenotype of Scer\GAL4^Bx-MS1096, rho-4^UAS.cUa

(Urban et al., 2002)

Suppressor of

Statement

Reference

S^UAS.cGa, Scer\GAL4^Act5C.PU is a suppressor of photoreceptor cell R1 | somatic clone phenotype of Gli::spi^{CS.s.spi.UAS.Tag:HA}, Scer\GAL4^Act5C.PU

(Steinhauer et al., 2013)

S^UAS.cGa is a suppressor of photoreceptor cell R2 | somatic clone phenotype of Gli::spi^{CS.s.spi.UAS.Tag:HA}

(Steinhauer et al., 2013)

S^UAS.cGa is a suppressor of photoreceptor cell R3 | somatic clone phenotype of Gli::spi^{CS.s.spi.UAS.Tag:HA}

(Steinhauer et al., 2013)

S^UAS.cGa is a suppressor of photoreceptor cell R4 | somatic clone phenotype of Gli::spi^{CS.s.spi.UAS.Tag:HA}

(Steinhauer et al., 2013)

S^UAS.cGa is a suppressor of photoreceptor cell R5 | somatic clone phenotype of Gli::spi^{CS.s.spi.UAS.Tag:HA}

(Steinhauer et al., 2013)

S^UAS.cGa is a suppressor of photoreceptor cell R6 | somatic clone phenotype of Gli::spi^{CS.s.spi.UAS.Tag:HA}

(Steinhauer et al., 2013)

S^UAS.cGa is a suppressor of photoreceptor cell R7 | somatic clone phenotype of Gli::spi^{CS.s.spi.UAS.Tag:HA}

(Steinhauer et al., 2013)

Other

Statement

Reference

Gli::spi^{CS.s.spi.UAS.Tag:HA}, S^UAS.cGa has photoreceptor cell R4 | ectopic | somatic clone phenotype

(Steinhauer et al., 2013)

Gli::spi^{CS.s.spi.UAS.Tag:HA}, S^UAS.cGa has photoreceptor cell R3 | ectopic | somatic clone phenotype

(Steinhauer et al., 2013)

Gli::spi^{CS.s.spi.UAS.Tag:HA}, S^UAS.cGa has photoreceptor cell R7 | ectopic | somatic clone phenotype

(Steinhauer et al., 2013)

Gli::spi^{CS.s.spi.UAS.Tag:HA}, S^UAS.cGa has photoreceptor cell R1 | ectopic | somatic clone phenotype

(Steinhauer et al., 2013)

Gli::spi^{CS.s.spi.UAS.Tag:HA}, S^UAS.cGa has photoreceptor cell R2 | ectopic | somatic clone phenotype

(Steinhauer et al., 2013)

Gli::spi^{CS.s.spi.UAS.Tag:HA}, S^UAS.cGa has photoreceptor cell R5 | ectopic | somatic clone phenotype

(Steinhauer et al., 2013)

Gli::spi^{CS.s.spi.UAS.Tag:HA}, S^UAS.cGa has photoreceptor cell R6 | ectopic | somatic clone phenotype

(Steinhauer et al., 2013)

S^UAS.cGa, Scer\GAL4^dpp.blk1, rho^UAS.cUa has eye disc morphogenetic furrow phenotype

(Kumar and Moses, 2001)

S^UAS.cGa, Scer\GAL4^ap-md544, spi^UAS.cSa has wing phenotype

(Pickup and Banerjee, 1999)

S^UAS.cGa, Scer\GAL4^ap-md544, spi^UAS.cSa has wing disc phenotype

(Pickup and Banerjee, 1999)

S^UAS.cGa, Scer\GAL4^ap-md544, spi^UAS.cSa has wing vein phenotype

(Pickup and Banerjee, 1999)

Additional Comments

Genetic Interactions

Statement

Reference

Expression of S^Scer\UAS.cGa suppresses the photoreceptor loss seen in clones expressing Gli::spi^{CS.s.spi.Scer\UAS.T:Ivir\HA1} under the control of Scer\GAL4^Act5C.PU. The resulting flies recruit ectopic photoreceptors.

(Steinhauer et al., 2013)

When Scer\GAL4^GMR.PF drives expression of both S^Scer\UAS.cGa and spi^Scer\UAS.cSa, the eye phenotype of S^Scer\UAS.cGa is strongly enhanced leading to smooth eyes with little or no red pugment and few mechanosensory bristles.

(Hsiung et al., 2001)

Expression of S^Scer\UAS.cGa and rho^Scer\UAS.cUa under the control of Scer\GAL4^dpp.blk1 results in ectopic furrow initiation in the eye disc.

(Kumar and Moses, 2001)

Coexpression of both S^Scer\UAS.cGa and spi^Scer\UAS.cSa using Scer\GAL4^ap-md544 results in ectopic proliferation of cells in the wing pouch of the wing disc and gives rise to wings which have blisters due to misapposition of the dorsal and ventral surfaces and which have missing and extra vein material.

(Pickup and Banerjee, 1999)

Xenogenetic Interactions

Statement

Reference

The mild wing vein phenotype generated by expression of Scer\GAL4^Bx-MS1096>Tcas\stet^{Scer\UAS.T:Avic\GFP} is enhanced by the co-expression of S^Scer\UAS.cGa.

The mild wing vein phenotype generated by expression of Scer\GAL4^Bx-MS1096>Tcas\stet^{Scer\UAS.T:Avic\GFP,T:Uuuu\KDEL} is enhanced by the co-expression of S^Scer\UAS.cGa.

(Rousso et al., 2010)

Complementation and Rescue Data

Rescues

Scer\GAL4^CY2/S^UAS.cGa rescues S^Kojak

(Ruden et al., 1999)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

S^Scer\UAS.cGa

S^UAS.cGa

Name Synonyms

Saccharomyces cerevisiae UAS construct a of Golembo

(Golembo et al., 1996)

Secondary FlyBase IDs

References (13)

Report Sections

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