FlyBase Allele Report: Dmel\Delta[eA7]

General Information

Symbol

Dmel\Delta^eA7

Species

D. melanogaster

Name

FlyBase ID

FBal0059138

Feature type

allele

Associated gene

Dmel\Delta

Associated Insertion(s)

Carried in Construct

Also Known As

Dl^eA7

Key Links

Allele class

Mutagen

ethyl methanesulfonate

Nature of the Allele

Allele class

Mutagen

ethyl methanesulfonate

(Verheyen et al., 1996)

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Verheyen et al., 1996)

visible | dominant

(Mahoney et al., 2006, Verheyen et al., 1996)

Phenotype Manifest In

wing

(Verheyen et al., 1996)

wing vein

(Mahoney et al., 2006)

wing vein | ectopic

(Mahoney et al., 2006)

Detailed Description

Statement

Reference

Heterozygotes show some wing vein thickening and have small amounts of ectopic vein on the wing.

(Mahoney et al., 2006)

Heterozygotes exhibit the characteristic Dl wing phenotype.

(Verheyen et al., 1996)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Delta^eA7 has visible | dominant phenotype, enhanceable by γTub23C[+]/γTub23C^bmps4

(Mahoney et al., 2006)

Enhancer of

Statement

Reference

Delta^eA7/Dl[+] is an enhancer of visible phenotype of Hipk³

(Lee et al., 2009)

Phenotype Manifest In

Enhanced by

Statement

Reference

Delta^eA7 has wing vein phenotype, enhanceable by γTub23C[+]/γTub23C^bmps4

(Mahoney et al., 2006)

Delta^eA7 has wing vein | ectopic phenotype, enhanceable by γTub23C[+]/γTub23C^bmps4

(Mahoney et al., 2006)

Enhancer of

Statement

Reference

Delta^eA7/Dl[+] is an enhancer of phenotype of Hipk²

(Lee et al., 2009)

Delta^eA7/Dl[+] is an enhancer of eye phenotype of Hipk³

(Lee et al., 2009)

Delta^eA7 is an enhancer of phenotype of N^nucl.sev

(Verheyen et al., 1996)

Additional Comments

Genetic Interactions

Statement

Reference

The severity of the small eye phenotype seen in hipk³ homozygotes is enhanced by Dl^eA7/+.

(Lee et al., 2009)

γTub23C^bmps4/+ enhances the wing vein thickening and amount of ectopic wing vein seen in Dl^eA7/+ flies.

(Mahoney et al., 2006)

Second site dominant enhancer of N^nucl.sev, eyes are small with a glossy, flat surface, often containing necrotic black spots.

(Verheyen et al., 1996)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Delta^eA7

Dl^eA7

(Lee et al., 2009, Mahoney et al., 2006)

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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