FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\BicDhs.PS
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General Information
Symbol
Dmel\BicDhs.PS
Species
D. melanogaster
Name
heat shock construct of Swan
FlyBase ID
FBal0059351
Feature type
allele
Associated gene
Dmel\BicD
Associated Insertion(s)
Carried in Construct
P{hsBic-D.scs}
Key Links
Transgenic product class
cDNA
(Swan and Suter, 1996)
wild_type
(Swan and Suter, 1996)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Swan and Suter, 1996)
wild_type
(Swan and Suter, 1996)
Mutagen
in vitro construct
(Swan and Suter, 1996)
Progenitor genotype
Carried in construct
P{hsBic-D.scs}
Cytology
Description

3.6kb ClaI-EcoRI fragment of BicD cDNA, which includes the entire open reading frame, is cloned behind an Hsp70 promoter, between scs and scs' boundary domains to minimize chromosomal position effects.

(Swan and Suter, 1996)
Allele components
Component
Use(s)
Regulatory region(s)
Hsp70
Encoded product / tool
BicD
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      BicDhs.PS rescues Df(2L)TW119/BicDr8

      (Swan and Suter, 1996)
      Comments

      Regular heat shock-induced expression of BicDhs.PS (two 37[o]C 30 minute heat shocks per day for 3-4 days starting in the late third larval instar/early pupal stage) is sufficient to overcome the lethality of the BicDr8/Df(2L)TW119 combination. Rescued adult females provided with regular heat shocks are fertile and lay mainly wild-type eggs.

      (Swan and Suter, 1996)
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      BicDhs.PS
      Name Synonyms
      heat shock construct of Swan
      (Swan and Suter, 1996)
      Secondary FlyBase IDs
        References (7)