FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\kelORF1.otu
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General Information
Symbol
Dmel\kelORF1.otu
Species
D. melanogaster
Name
FlyBase ID
FBal0060380
Feature type
allele
Associated gene
Dmel\kel
Associated Insertion(s)
Carried in Construct
P{kel.ORF1}
Key Links
Transgenic product class
inframe_deletion
(Robinson and Cooley, 1997)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Robinson and Cooley, 1997)
Mutagen
in vitro construct
(Robinson and Cooley, 1997)
Progenitor genotype
Carried in construct
P{kel.ORF1}
Cytology
Description

Construct: A truncated kel cDNA fragment (encoding the 76kD ORF1 kel protein) is expressed under the control of an otu promoter (nucleotides 1 to 740 of the genomic sequence in FBrf0050545). The fs(1)K10 3' untranslated region containing transcription termination sequences is fused to the 3' end of the kel cDNA fragment.

(Robinson and Cooley, 1997)
Allele components
Component
Use(s)
Regulatory region(s)
otu
Encoded product / tool
kel
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Hemizygous kelDE1 flies carrying kelORF1.otu produce eggs at nearly wild-type rates. kelneo2/kelPL25 flies carrying kelORF1.otu produce eggs at approximately wild-type rates.

      (Robinson and Cooley, 1997)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      kelORF1.otu rescues kelDE1

      (Kelso et al., 2002)

      kelORF1.otu rescues kelDE1

      (Robinson and Cooley, 1997)

      kelORF1.otu rescues kelneo2

      (Robinson and Cooley, 1997)
      Comments

      Nurse cell ring canal diameter in kelDE1 homozygotes is completely rescued by kelORF1.otu.

      (Kelso et al., 2002)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      kelORF1.otu
      Name Synonyms
      Secondary FlyBase IDs
        References (4)