FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Mmus\Lef1UAS.Tag:T7
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General Information
Symbol
Mmus\Lef1UAS.Tag:T7
Species
M. musculus
Name
Saccharomyces cerevisiae UAS construct a of Riese
FlyBase ID
FBal0060605
Feature type
allele
Associated gene
Mmus\Lef1
Associated Insertion(s)
Carried in Construct
P{UAS.LEF-1}
Transgenic product class
wild_type
(Riese et al., 1997)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Riese et al., 1997)
Mutagen
in vitro construct
(Riese et al., 1997)
Progenitor genotype
Carried in construct
P{UAS.LEF-1}
Cytology
Description

UASt regulatory sequences drive expression of the Mmus\Lef1 coding sequence, tagged at the C-terminal end with Tag:T7.

(Riese et al., 1997)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Mmus\Lef1
Tagged with
Tag:T7
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Dorsal clones in the tarsus expressing Scer\GAL4Act5C.PI-driven Mmus\Lef1Scer\UAS.cRa are normal. Clones in the ventral-most rows often show transformation towards more dorsal fates.

      (Svendsen et al., 2009)

      Scer\GAL4Bx-MS1096-mediated expression causes ectopic bristles on the notum near the dorsocentral and postalar bristles. Bristle tufts and individual ectopic bristles appear at the wing tip and near the anterior wing margin or hinge. Stretches of the wing margin are also missing.

      (Riese et al., 1997)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      Clones expressing both midScer\UAS.cBa and Mmus\Lef1Scer\UAS.cRa in the tarsus driven by Scer\GAL4bi-omb-Gal4 are recovered more often in lateral and dorsal cells, indicating altered sorting behaviour. Dorsolateral clones expressing both midScer\UAS.cBa and Mmus\Lef1Scer\UAS.cRa do not transform towards ventral fate, whereas ventrolateral clones do so sometimes.

      (Svendsen et al., 2009)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Expressed in embryos to study stimulation of Ecol\lacZ expression from Ubx promoter fragments containing the Mmus\Lef1 binding site.

      (Riese et al., 1997)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      Mmus\Lef1Scer\UAS.cRa
      Mmus\Lef1UAS.Tag:T7
      Mmus\Lef1UAS.cRa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Riese
      (Riese et al., 1997)
      Secondary FlyBase IDs
        References (3)