FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\pum06897
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General Information
Symbol
Dmel\pum06897
Species
D. melanogaster
Name
FlyBase ID
FBal0060925
Feature type
allele
Associated gene
Dmel\pum
Associated Insertion(s)
P{PZ}pum06897
Carried in Construct
Also Known As
pum6897
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Lin and Spradling, 1997)
Progenitor genotype
Associated Insertion(s)
P{PZ}pum06897
Cytology
Description

The P{lacW} transposon in inserted between exons 8 and 9 on the pum transcription unit.

(Schweers et al., 2002)

P{PZ} insertion in the intron between exons 8 and 9. The orientation of the P{PZ} element is such that the ry marker gene is towards the 5' side of the pum gene while the Ecol\lacZ gene is oriented towards the 3' side.

(Parisi and Lin, 1999)
Allele components
Component
Use(s)
Inserted element
P{PZ}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      More than 50% of homozygous larvae survive the pupal stage to eclosion. 54% of homozygous ovaries from third instar larvae have an underproliferated germline, 23% have a normal number of germline cells and 23% have an overproliferated germline. The germ cells are grossly abnormal in morphology and size and the ovary is much larger than in wild-type larvae. By the midpupal stage, individual germaria have formed (as in wild type) but 63% of them do not contain germline cells and the remaining mutant ovarioles contain a small number of germline cells. By the adult stage, 86% of homozygous females have germlineless ovaries, 7% have "differentiated ovaries" (containing recognisable egg chambers and/or germline cells in at least one ovariole) and 7% of females have one germlineless and one differentiated ovary.

      (Parisi and Lin, 1999)

      Small ovary phenotype.

      (Lin and Spradling, 1997)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      pum07098 and pum06897 have identical P{PZ} insertion sites.

      (Parisi and Lin, 1999)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      fs(3)06897
      pum06897
      pum6897
      (Parisi and Lin, 1999, Lin and Spradling, 1997)
      pumovt
      (Schweers et al., 2002)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)