FB2026_02 , released June 18, 2026
Allele: Dmel\escr4
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General Information
Symbol
Dmel\escr4
Species
D. melanogaster
Name
FlyBase ID
FBal0061440
Feature type
allele
Associated gene
Dmel\esc
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Hemizygous mxcM1 males show weak homeotic phenotypes. No significant interaction is detected in mxcM1/Y in trans with one mutant copy of escr4.

        (Saget et al., 1998)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Suppressor of
        Statement
        Reference

        escr4 is a suppressor of abnormal eye color phenotype of wT81

        (Netter et al., 1998)
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        No significant modification of the number of sex combs is seen in escr4/+ corto420/+ double heterozygotes compared to escr4/+ single heterozygotes.

        (Lopez et al., 2001)

        Weak suppressor of eye pigment phenotype of wT81.

        (Netter et al., 1998)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        escr4
        Name Synonyms
        Secondary FlyBase IDs
          References (7)