FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Allele: Dmel\Lk6Ubi-p63E.PK
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General Information
Symbol
Dmel\Lk6Ubi-p63E.PK
Species
D. melanogaster
Name
Ubiquitin-63E promoter construct of Kidd
FlyBase ID
FBal0061740
Feature type
allele
Associated gene
Dmel\Lk6
Associated Insertion(s)
Carried in Construct
P{PUBq-LK6}
Key Links
Transgenic product class
cDNA
(Kidd and Raff, 1997)
wild_type
(Kidd and Raff, 1997)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Kidd and Raff, 1997)
wild_type
(Kidd and Raff, 1997)
Mutagen
in vitro construct
(Kidd and Raff, 1997)
Progenitor genotype
Carried in construct
P{PUBq-LK6}
Cytology
Description

An Lk6 cDNA is expressed under the control of a Ubi-p63E promoter.

(Kidd and Raff, 1997)
Allele components
Component
Use(s)
Regulatory region(s)
Ubi-p63E
Encoded product / tool
Lk6
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Flies carrying Lk6Ubi-p63E.PK are very unhealthy. 20-50% of the eggs laid by females carrying Lk6Ubi-p63E.PK are unfertilised and have defects in microtubule formation. Only 30-50% of the eggs laid by females carrying Lk6Ubi-p63E.PK hatch. These embryos have a number of mitotic defects. Most of the surviving larvae pupate, and approximately 60-70% of the pupae eclose as adults. The hatching rate is not rescued by mating females carrying Lk6Ubi-p63E.PK to control males. Control females mated to males carrying Lk6Ubi-p63E.PK have normal hatching rates.

      (Kidd and Raff, 1997)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Lk6Ubi-p63E.PK
      Name Synonyms
      Ubiquitin-63E promoter construct of Kidd
      (Kidd and Raff, 1997)
      Secondary FlyBase IDs
        References (1)