Only a small percentage of homozygotes survive to adulthood. These adult flies have a range of morphological defects, including rough eyes (due to missing ommatidia), missing bristles (particularly humeral bristles) and disruptions in abdominal structures (particularly in female flies). Movement is not well coordinated and homozygous flies tend to die earlier than heterozygous siblings. Homozygous females have reduced fertility, and lay few if any eggs. The ovaries are generally small and produce a reduced number of mature oocytes. Homozygous males appear to be sterile, although there are few if any meiotic defects in the testes and motile sperm are produced. Homozygous progeny of homozygous females die either during embryonic or early larval stages. Larval brains contain polyploid figures, although the frequency of mitotic cells and anaphase cells is normal. Some polyploid follicle cells are seen in the ovaries of homozygous females, and larger follicle cells which often contain two nuclei are seen.