FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\mamunspecified
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General Information
Symbol
Dmel\mamunspecified
Species
D. melanogaster
Name
FlyBase ID
FBal0062570
Feature type
allele
Associated gene
Dmel\mam
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description

    FlyBase curator comment: this entry is used to capture phenotypic information when the particular allele (or allele combination) used by the author could not be determined but the context of the experiment suggests that the phenotype being described is some kind of loss of function.

    (FlyBase Curators, 2025-)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Mutants show an increased number of tendon cells at late stages of embryonic development (after muscle binding has occurred) compared to wild type.

        (Nabel-Rosen et al., 1999)

        Homozygous clones in the wing produce discrete, round blisters of variable size. These blisters can be located anywhere on the wing and are associated with abnormalities in venation. Homozygous clones that include the wing margin cause scalloping due to cell death.

        (Prout et al., 1997)

        mamunspecified mutant embryos show hypertrophy of the central nervous system. A maternal effect is seen in germline clones.

        (Tearle and Nusslein-Volhard, 1987)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Enhancer of
        Statement
        Reference

        mamunspecified/mam[+] is an enhancer of visible | recessive phenotype of mys8

        (Prout et al., 1997)
        Phenotype Manifest In
        Enhancer of
        Statement
        Reference

        mamunspecified/mam[+] is an enhancer of wing phenotype of mys8

        (Prout et al., 1997)
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        Shows a weak genetic interaction with mys8; the frequency of wing blisters is increased from approximately 10% in mys8 single hemizygotes to approximately 20% in mys8 hemizygotes that are also heterozygous for mamunspecified. Shows no interaction with mysb9.

        (Prout et al., 1997)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        mamunspecified
        unspecified
        (Prout et al., 1997)
        Name Synonyms
        Secondary FlyBase IDs
          References (5)