FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\ecd3D
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General Information
Symbol
Dmel\ecd3D
Species
D. melanogaster
Name
FlyBase ID
FBal0062870
Feature type
allele
Associated gene
Dmel\ecd
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
gamma ray
(Henrich et al., 1993)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In

      macrochaeta & adult thorax

      (Henrich et al., 1993)
      Detailed Description
      Statement
      Reference

      ecd3D causes death prior to the completion of embryogenesis when inherited maternally, but has a negligible effect on embryonic survival when inherited paternally. ecd3D causes death prior to the adult stage among a large proportion of heterozygotes when inherited from either parent. Only 0.7% of eggs from a cross between ecd3D/+ females and ecd1/+ males hatch as ecd1/ecd3D larvae at 29oC. These infrequent survivors die shortly after hatching. 7.3% of eggs from a cross between ecd3D/+ males and ecd1/+ females hatch as ecd1/ecd3D larvae at 29oC. Only a small fraction of oocytes mature into eggs in the ovaries of heterozygous females kept at 29oC. The number of macrochaetae on the thorax is reduced in ecd1/ecd3D flies kept at 29oC in the hours that follow prepupal formation.

      (Henrich et al., 1993)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Other
      Statement
      Reference

      ecd3D, l(3)62Da1 has lethal phenotype

      (Henrich et al., 1993)

      ecd3D, slsg72 has lethal phenotype

      (Henrich et al., 1993)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      slsg72/ecd3D double heterozygotes die shortly after prepupal formation. l(3)62Da1/ecd3D double heterozygotes die in the mid-third larval instar stage.

      (Henrich et al., 1993)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      ecd2

      (Henrich et al., 1993)

      ecd1

      (Henrich et al., 1993)
      Comments

      Fails to complement ecd1 at 29oC, although ecd1/ecd3D animals complete development at 18oC.

      (Henrich et al., 1993)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      ecd3D
      Name Synonyms
      Secondary FlyBase IDs
        References (1)