FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Sema2ak11240
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General Information
Symbol
Dmel\Sema2ak11240
Species
D. melanogaster
Name
FlyBase ID
FBal0063768
Feature type
allele
Associated gene
Dmel\Sema2a
Associated Insertion(s)
P{lacW}Sema2ak11240
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Roch et al., 1998, BDGP Project Members, 1994-1999)
Progenitor genotype
Associated Insertion(s)
P{lacW}Sema2ak11240
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{lacW}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Sema2a03474/Sema2ak11240 transheterozygous embryos show high frequency of defects in the salivary gland (the distal end of the SG which normally contacts the VIS5 muscle is often directed away from the muscle) compared to wild-type controls.

      (Hanlon and Andrew, 2016)

      Lethality occurs during third instar larval or pupal stages. Mutants exhibit visible disc abnormalities: very small or no discs. Clones cannot be induced in wild type discs.

      (Roch et al., 1998)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      Sema2a03021

      (BDGP Project Members, 1994-1999)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer

      I. Kiss.

      (BDGP Project Members, 1994-1999)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (5)
      Reported As
      Symbol Synonym
      112/40
      (Roch et al., 1998)
      Sema-2ak11240
      (Hanlon and Andrew, 2016)
      Sema2ak11240
      (BDGP Project Members, 1994-1999)
      l(2)k11240
      (Spradling et al., 1999)
      sema-IIk11240
      Name Synonyms
      Secondary FlyBase IDs
        References (6)