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General Information
Symbol
Dmel\Lack11012b
Species
D. melanogaster
Name
FlyBase ID
FBal0064190
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
bulbk11012b
Key Links
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Mutation has no obvious effect on the morphology of the salivary gland or hindgut. Early tracheal development, including primary branch budding and outgrowth and lumen formation and morphology occur normally during stages 11-14. Stage 16 embryos show a number of tracheal defects. These include an increased length of the dorsal trunk compared to wild type (with no accompanying increase in cell number), mild defects in the diameter of the dorsal trunk and moderate defects in the diameter of other primary branches. Irregular and variable tracheal tube morphologies, with local constrictions and/or dilations are seen in all major branches. The defects are first seen at stage 15.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

Lack11012b/LacBG01462 embryos have a similar tracheal phenotype to LacBG01462 homozygotes.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Not rescued by
Fails to rescue
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer

Separable from: P{lacW}k11012a. The Lack11012b mutation is separable from the P{lacW}k11012a insertion.

Comments
Comments

Complements: shotk03010. Complements: shotk05405. Complements: shot2. Complements: shot5. Complements: mam03751. Complements: mam2.

Complements: upok05916. Complements: l(2)k06904k06904. Complements: l(2)k01209k08901a. Complements: l(2)k01209k14501. Complements: cnkk16314.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (6)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (7)