FlyBase Allele Report: Dmel\bic[k10712]

General Information

Symbol

Dmel\bic^k10712

Species

D. melanogaster

Name

FlyBase ID

FBal0064199

Feature type

allele

Associated gene

Dmel\bic

Associated Insertion(s)

P{lacW}bic^k10712

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Roch et al., 1998, BDGP Project Members, 1994-1999)

Progenitor genotype

Associated Insertion(s)

P{lacW}bic^k10712

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{lacW}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

2R:12,870,220..12,870,220 [+]

(Beaton, 2000.1.31, Spradling et al., 1999, Roch et al., 1998, BDGP Project Members, 1994-1999)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Braat et al., 2004, Beaton, 2000.1.31, Spradling et al., 1999, Roch et al., 1998)

Phenotype Manifest In

imaginal disc

(Roch et al., 1998)

Detailed Description

Statement

Reference

Lethality occurs during third instar larval or pupal stages. Mutants exhibit visible disc abnormalities: very small or no discs. Clones cannot be induced in wild type discs. In tergites, clones with normal size and frequency are recovered. Clones cannot be recovered in the wing disc.

(Roch et al., 1998)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

10998

y¹ w^67c23; P{lacW}bic^k10712/CyO

Kyoto

111293

y^d2 w¹¹¹⁸ P{ey-FLP.N}2 P{5xglBS-lacZ.38-1}TPN1; P{neoFRT}42D P{lacW}bic^k10712 /CyO y⁺

Notes on Origin

Discoverer

I. Kiss.

(BDGP Project Members, 1994-1999)

Comments

Reversion analysis proved that the P{lacW} is responsible for the lethal phenotype.

(Beaton, 2000.1.31)

Complements: l(2)01424⁰¹⁴²⁴. Complements: Nacα⁰⁴³²⁹. Complements: Aats-asp^k04508. Complements: l(2)k05722^k05722. Complements: l(2)k09328^k09328. Complements: l(2)rQ029^rQ029.

(BDGP Project Members, 1994-1999)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (6)

Reported As

Symbol Synonym

107/12

(Roch et al., 1998)

Btf^k10712

bic^K10712

(Yamada et al., 2023)

bic^k10712

l(2)k10712

(Spradling et al., 1999)

l(2)k10712^k10712

(BDGP Project Members, 1994-1999)

Name Synonyms

Secondary FlyBase IDs

References (6)

Report Sections

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