FlyBase Allele Report: Dmel\snRNA:U4:39B[k09414]

General Information

Symbol

Dmel\snRNA:U4:39B^k09414

Species

D. melanogaster

Name

FlyBase ID

FBal0064271

Feature type

allele

Associated gene

Dmel\snRNA:U4:39B

Associated Insertion(s)

P{lacW}snRNA:U4:39B^k09414

Carried in Construct

Key Links

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(BDGP Project Members, 1994-1999)

Progenitor genotype

Associated Insertion(s)

P{lacW}snRNA:U4:39B^k09414

Cytology

Description

No sequence data is available for the P{lacW}snRNA:U4:39B^k09414 line. The P{lacW}snRNA:U4:39B^k09414 insertion line was designated an allele of snRNA:U4:39B in FlyBase based on its failure to complement the lethality of the P{lacW}snRNA:U4:39B^k09410 insertion line. However, since the P{lacW}snRNA:U4:39B^k09410 insertion maps within both snRNA:U4:39B and Atg18b (nested genes), it is unclear to which transcription unit the lethality maps. It is therefore unknown whether the P{lacW}snRNA:U4:39B^k09414 insertion line causes an allele of snRNA:U4:39B or Atg18b or both. Alleles of both genes have been made in FlyBase for the P{lacW}snRNA:U4:39B^k09414 insertion line until more information is known.

(FlyBase, 1992-)

Allele components

Component

Use(s)

Inserted element

P{lacW}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(BDGP Project Members, 1994-1999)

Phenotype Manifest In

Detailed Description

Statement

Reference

FlyBase curator comment: the P{lacW}snRNA:U4:39B^k09414 insertion results in homozygous lethality, but it is unclear whether the lethality is due to an effect on snRNA:U4:39B or CG8678 (or both) (see FBrf0105495).

(BDGP Project Members, 1994-1999)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

snRNA:U4:39B^k09410

(BDGP Project Members, 1994-1999)

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Kyoto

102708

y¹ w^67c23 ; P{lacW}snRNA:U4:39B^k09414 / CyO

Notes on Origin

Discoverer

I. Kiss.

(BDGP Project Members, 1994-1999)

Comments

This allele was listed in the BDGP database as a lethal or sterile line during the period 1994-1999, but was discarded from the gene disruption project prior to the summary publication (FBrf0111489). Reasons for excluding lines from the collection described in FBrf0111489 include presence of more than one P insertion on the mutant chromosome, separation of lethality (or sterility) from the location of the insertion, and loss of lethality (or sterility) from the stock. Further information is available from http://www.fruitfly.org/bfd/ and from Dr. Spradling (spradling@mail1.ciwemb.edu).

Complements: bur¹⁰⁵²³.

(BDGP Project Members, 1994-1999)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

l(2)k09410^k09414

(BDGP Project Members, 1994-1999)

snRNA:U4:39B^k09414

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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