FlyBase Allele Report: Dmel\wal[k14036]

General Information

Symbol

Dmel\wal^k14036

Species

D. melanogaster

Name

FlyBase ID

FBal0064758

Feature type

allele

Associated gene

Dmel\wal

Associated Insertion(s)

P{lacW}wal^k14036

Carried in Construct

Key Links

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(BDGP Project Members, 1994-1999)

Progenitor genotype

Associated Insertion(s)

P{lacW}wal^k14036

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{lacW}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal - all die during embryonic stage | recessive

(Liu et al., 1999)

some die during embryonic stage | recessive

(Liu et al., 1999)

Phenotype Manifest In

embryonic/larval esophagus | embryonic stage

(Liu et al., 1999)

embryonic/larval pharynx | embryonic stage

(Liu et al., 1999)

embryonic/larval proventriculus | embryonic stage

(Liu et al., 1999)

embryonic/larval tracheal section

(Liu et al., 1999)

embryonic head

(Liu et al., 1999)

embryonic Malpighian tubule

(Liu et al., 1999)

embryonic midgut constriction

(Liu et al., 1999)

Malpighian tubule primordium

(Liu et al., 1999)

Detailed Description

Statement

Reference

Embryos show early defects in Malpighian tubule bud evagination and later have convoluted Malpighian tubules. Proventriculus morphogenesis and pharynx invagination are incomplete and embryos have a wide, corrugated oesophagus. Midgut constrictions do not form. Head involution is incomplete and tracheae are abnormal.

(Liu et al., 1999)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

wal⁰²⁵¹⁶

(Liu et al., 1999)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

I. Kiss.

(BDGP Project Members, 1994-1999)

Comments

This allele was listed in the BDGP database as a lethal or sterile line during the period 1994-1999, but was discarded from the gene disruption project prior to the summary publication (FBrf0111489). Reasons for excluding lines from the collection described in FBrf0111489 include presence of more than one P insertion on the mutant chromosome, separation of lethality (or sterility) from the location of the insertion, and loss of lethality (or sterility) from the stock. Further information is available from http://www.fruitfly.org/bfd/ and from Dr. Spradling (spradling@mail1.ciwemb.edu).

The phenotype is reverted by excision of the P{lacW} element.

(Liu et al., 1999)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

k14036

(Liu et al., 1999)

l(2)02516^k14036

wal^k14036

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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