FlyBase Allele Report: Dmel\osk[bcd.3UTR.A7]

General Information

Symbol

Dmel\osk^bcd.3UTR.A7

Species

D. melanogaster

Name

FlyBase ID

FBal0065721

Feature type

allele

Associated gene

Dmel\osk

Associated Insertion(s)

Carried in Construct

P{osk^bcd.3UTR.A7}

Key Links

Transgenic product class

wild_type

(Webster et al., 1997)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Webster et al., 1997)

Mutagen

in vitro construct

(Webster et al., 1997)

Progenitor genotype

Carried in construct

P{osk^bcd.3UTR.A7}

Cytology

Description

Construct: Fragment containing the osk promoter, the entire osk coding region and the first 535bp of the osk 3' UTR (which contains multiple aret response element (BRE) consensus sequences), followed by a fragment of the bcd 3' UTR which contains anterior localisation signals.

(Webster et al., 1997)

Allele components

Component

Use(s)

Encoded product / tool

osk

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

cephalopharyngeal skeleton

(Webster et al., 1997)

Detailed Description

Statement

Reference

Embryos derived from females carrying osk^bcd.3UTR.A7 have head defects, including a reduction in the cephalopharyngeal skeleton.

(Webster et al., 1997)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Enhanced by

Statement

Reference

osk^bcd.3UTR.A7 has embryo | anterior phenotype, enhanceable by bru1^QB

(Webster et al., 1997)

Additional Comments

Genetic Interactions

Statement

Reference

This phenotype is enhanced if the mother is also heterozygous for aret^QB; embryos derived from aret^QB/+ ; osk^bcd.3UTR.A7 females have extensive anterior deletions, often accompanied by duplication of posterior pattern elements. The phenotype is also enhanced by Df(2L)esc-P3-0.

(Webster et al., 1997)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

osk^bcd.3UTR.A7

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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