FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\heprh99
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General Information
Symbol
Dmel\heprh99
Species
D. melanogaster
Name
FlyBase ID
FBal0065838
Feature type
allele
Associated gene
Dmel\hep
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Some of the hemizygous males rescued by Mmus\Prkmk7Ubi-p63E.PH are fully fertile and viable, but the majority of adult males have defects in the dorsal thorax and in the development and rotation of the anal plate and genital arches.

        (Holland et al., 1997)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Suppressed by
        Statement
        Reference

        heprh99 has lethal | recessive phenotype, suppressible by Mmus\Map2k7Ubi-p63E.PH

        (Holland et al., 1997)

        heprh99 has lethal | recessive phenotype, suppressible by Mmmm\Sek1Ubi-p63E.PH

        (Holland et al., 1997)

        heprh99 has lethal | recessive phenotype, suppressible by Xlae\map2k4.LUbi-p63E.PH

        (Holland et al., 1997)
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference

        The lethality of hemizygous males is rescued by Mmus\Prkmk7Ubi-p63E.PH in 42% of cases. Some of the males produced are fully fertile and viable, but the majority of adult males have defects in the dorsal thorax and in the development and rotation of the anal plate and genital arches. The lethality of hemizygous males is rescued by Mmmm\Sek1Ubi-p63E.PH in 14% of cases and by Xlae\Mek2Ubi-p63E.PH in 15% of cases.

        (Holland et al., 1997)
        Complementation and Rescue Data
        Rescued by

        heprh99 is rescued by hepUbi-p63E.PG

        (Holland et al., 1997)
        Comments

        The lethality of hemizygous males is rescued by hepUbi-p63E.PG, giving rise to viable, fertile adults in 96% of cases.

        (Holland et al., 1997)
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        heprh99
        Name Synonyms
        Secondary FlyBase IDs
          References (1)