FB2026_03 , released September 17, 2026
Allele: Dmel\stich1S143702
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General Information
Symbol
Dmel\stich1S143702
Species
D. melanogaster
Name
FlyBase ID
FBal0082209
Feature type
allele
Associated gene
stich1
Associated Insertion(s)
P{lacW}stich1S143702
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
Delta2-3 transposase
(Deak et al., 1997)
P-element activity
(Dubruille et al., 2002, Prokopenko et al., 2000, Szeged Stock Center, 1998-, Deak et al., 1997, Salzberg et al., 1997)
Progenitor genotype
Associated Insertion(s)
P{lacW}stich1S143702
Caused by aberration
Df(3R)S143702
Cytology
Description

P{lacW} insertion in the jumu gene associated with a deficiency which removes both Rfx and jumu coding regions.

(Dubruille et al., 2002)

Flanking sequence recovered from either side of the P{lacW} insertion in stich1S143702 are located at least 28kb apart on the genomic sequence. This suggests that there may be 2 different P{lacW} elements that map 28kb apart in the "l(3)S143702" line, or the P{lacW}stich1S143702 insertion may be associated with a 28kb deletion. One set of flanking sequence indicates that the P{lacW} element is inserted approximately 90bp upstream of the 5' end of the GM05287 cDNA. The other set of flanking sequence maps within the first intron of jumu, suggesting that both GM05287 and jumu may be affected in the "l(3)S143702" line.

(Prokopenko et al., 2000)
Allele components
Component
Use(s)
Inserted element
P{lacW}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
AF175945
AF175946
AF175947
AF175948
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Early lethal.

      (Deak et al., 1997)

      Embryos exhibit loss of neurons in v and v' clusters and a change in morphology of the remaining neurons.

      (Salzberg et al., 1997)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      stich1EP359

      (Prokopenko et al., 2000)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      P{lacW} element can be reverted. Complements: jumu06142a. Complements: l(3)j8B6j8B6.

      (Prokopenko et al., 2000)

      In reversion analysis, P{lacW}stich1S143702 does not excise to restore viability to the chromosome.

      (Salzberg et al., 1997)
      External Crossreferences and Linkouts ( 4 )
      Crossreferences
      GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      1437/02
      (Deak et al., 1997)
      1437/2
      (Salzberg et al., 1997)
      l(3)S143702
      (Prokopenko et al., 2000)
      stich1S143702
      Name Synonyms
      Secondary FlyBase IDs
        References (6)