FlyBase Allele Report: Dmel\Delta[S130403]

General Information

Symbol

Dmel\Delta^S130403

Species

D. melanogaster

Name

FlyBase ID

FBal0083541

Feature type

allele

Associated gene

Dmel\Delta

Associated Insertion(s)

P{lacW}Delta^S130403

Carried in Construct

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Delta2-3 transposase

(Deak et al., 1997)

P-element activity

(Salzberg et al., 1997)

Progenitor genotype

Associated Insertion(s)

P{lacW}Delta^S130403

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{lacW}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Deak et al., 1997)

lethal - all die during embryonic stage | recessive

(Salzberg et al., 1997)

some die during embryonic stage | recessive

(Salzberg et al., 1997)

Phenotype Manifest In

presumptive embryonic/larval central nervous system

(Salzberg et al., 1997)

presumptive embryonic/larval peripheral nervous system

(Salzberg et al., 1997)

Detailed Description

Statement

Reference

Early lethal.

(Deak et al., 1997)

Embryos exhibit hypertrophy of PNS and CNS.

(Salzberg et al., 1997)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Dl^S130403 is a dominant enhancer of the mild rough eye phenotype of In(1)rst³.

(Gorski et al., 2000)

Dominant enhancer of the rough eye phenotype of In(1)rst³.

(Tanenbaum et al., 2000)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

Δ2-3 induced reversion demonstrates the insertion is responsible for the lethal phenotype.

(Salzberg et al., 1997)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

1304/03

(Deak et al., 1997)

1304/3

(Salzberg et al., 1997)

Delta^S130403

Dl^S130403

(Gorski et al., 2000)

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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