FlyBase Allele Report: Dmel\CycA[S004024]

General Information

Symbol

Dmel\CycA^S004024

Species

D. melanogaster

Name

FlyBase ID

FBal0083573

Feature type

allele

Associated gene

Dmel\CycA

Associated Insertion(s)

P{lacW}CycA^S004024

Carried in Construct

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Delta2-3 transposase

(Deak et al., 1997)

P-element activity

(Szeged Stock Center, 1998-, Salzberg et al., 1997)

Progenitor genotype

Associated Insertion(s)

P{lacW}CycA^S004024

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{lacW}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Szeged Stock Center, 1998-, Salzberg et al., 1997)

partially lethal - majority die | recessive

(Deak et al., 1997)

some die during immature adult stage | recessive

(Salzberg et al., 1997)

Phenotype Manifest In

neuron | embryonic stage

(Salzberg et al., 1997)

Detailed Description

Statement

Reference

Embryos exhibit reduced number of neurons, the remaining cells are enlarged.

(Salzberg et al., 1997)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhancer of

Statement

Reference

CycA^S004024 is a non-enhancer of visible phenotype of Ret^MEN2B.GMR

(Read et al., 2005)

NOT Suppressor of

Statement

Reference

CycA^S004024 is a non-suppressor of visible phenotype of Ret^MEN2B.GMR

(Read et al., 2005)

Phenotype Manifest In

NOT Enhancer of

Statement

Reference

CycA^S004024 is a non-enhancer of eye phenotype of Ret^MEN2B.GMR

(Read et al., 2005)

NOT Suppressor of

Statement

Reference

CycA^S004024 is a non-suppressor of eye phenotype of Ret^MEN2B.GMR

(Read et al., 2005)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

Δ2-3 induced reversion demonstrates the insertion is responsible for the lethal phenotype.

(Salzberg et al., 1997)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

0040/24

(Deak et al., 1997)

40/24

(Salzberg et al., 1997)

CycA^S004024

l(3)S004024

(Read et al., 2005)

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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