FB2026_02 , released June 18, 2026
Allele: Dmel\Snap25hs.PW
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General Information
Symbol
Dmel\Snap25hs.PW
Species
D. melanogaster
Name
heat shock construct of Wu
FlyBase ID
FBal0085913
Feature type
allele
Associated gene
Dmel\Snap25
Associated Insertion(s)
Carried in Construct
P{hs-Snap25.W}
Key Links
Transgenic product class
cDNA
(Wu et al., 1998)
wild_type
(Wu et al., 1998)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Wu et al., 1998)
wild_type
(Wu et al., 1998)
Mutagen
in vitro construct
(Wu et al., 1998)
Progenitor genotype
Carried in construct
P{hs-Snap25.W}
Cytology
Description

Full length Snap25 cDNA is expressed under the control of an Hsp70 promoter.

(Wu et al., 1998)
Allele components
Component
Use(s)
Regulatory region(s)
Hsp70
Encoded product / tool
Snap25
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Flies carrying Snap25hs.PW are viable and have normal wings and eyes at 25oC.

      (Nie et al., 1999)

      Overexpression of Snap25hs.PW causes no defects in either the amplitude of the excitatory junctional potential (EJP), or the frequency of miniature EJPs in the muscle at the larval neuromuscular junction. Snap25hs.PW does not alter the physiological defects seen in the muscle at the larval neuromuscular junction of flies overexpressing Rophs.PS when coexpressed with Rophs.PS.

      (Wu et al., 1998)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Snap25hs.PW
      Name Synonyms
      heat shock construct of Wu
      (Wu et al., 1998)
      Secondary FlyBase IDs
        References (2)