FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\fjhs.PB
Open Close
General Information
Symbol
Dmel\fjhs.PB
Species
D. melanogaster
Name
heat shock construct of Buckles
FlyBase ID
FBal0086625
Feature type
allele
Associated gene
Dmel\fj
Associated Insertion(s)
Carried in Construct
P{hsp70-fj.B}
Key Links
Transgenic product class
cDNA
(Buckles et al., 2001)
wild_type
(Buckles et al., 2001)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Buckles et al., 2001)
wild_type
(Buckles et al., 2001)
Mutagen
in vitro construct
(Buckles et al., 2001, Buckles et al., 1998)
Progenitor genotype
Carried in construct
P{hsp70-fj.B}
Cytology
Description

An Hsp70 promoter drives expression of a 2.2kb cDNA fragment containing the entire fj open reading frame.

(Buckles et al., 2001)
Allele components
Component
Use(s)
Regulatory region(s)
Hsp70
Encoded product / tool
fj
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      An ectopic joint-like structure is present in 80.5% of legs in flies expressing fjhs.PB. The ectopic partial joints appear as doughnut-shaped invaginations in tarsal segment 3, or much less frequently in tarsal segments 2 and 4, and are usually in the middle of the segment. The ectopic joints are formed with minimal loss of growth in the segment and no loss of endogenous joints.

      (Buckles et al., 2001)

      Flies expressing fjhs.PB show patterning defects in the wings, eyes, optic projections, and legs.

      (Buckles et al., 1998)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Carried in plasmid "pHS-fj+", transfected into S2 cells and used to study the subcellular localisation of the fj protein.

      (Buckles et al., 2001)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      fjhs.PB
      Name Synonyms
      heat shock construct of Buckles
      (Buckles et al., 1998)
      Secondary FlyBase IDs
        References (2)