FlyBase Allele Report: Dmel\Antp[UAS.cMa]

General Information

Symbol

Dmel\Antp^UAS.cMa

Species

D. melanogaster

Name

Saccharomyces cerevisiae UAS construct a of Moreno

FlyBase ID

FBal0086922

Feature type

allele

Associated gene

Dmel\Antp

Associated Insertion(s)

Carried in Construct

P{UAS-Antp.M}

Also Known As

UAS-Antp

Key Links

Transgenic product class

wild_type

(Azpiazu and Morata, 1998)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Azpiazu and Morata, 1998)

Mutagen

in vitro construct

(Azpiazu and Morata, 1998)

Progenitor genotype

Carried in construct

P{UAS-Antp.M}

Cytology

Description

UAS regulatory sequences drive expression of Antp.

(Azpiazu and Morata, 1998)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Antp

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

homeotic, with Scer\GAL4^arm.PS

(Noro et al., 2011)

Phenotype Manifest In

embryonic/first instar larval cuticle, with Scer\GAL4^arm.PS

(Gebelein et al., 2002)

Keilin organ, with Scer\GAL4^arm.PS

(Gebelein et al., 2002)

larval mesothoracic segment | ectopic, with Scer\GAL4^arm.PS

(Noro et al., 2011)

larval prothoracic segment, with Scer\GAL4^arm.PS

(Noro et al., 2011)

ventral denticle belt, with Scer\GAL4^arm.PS

(Gebelein et al., 2002)

Detailed Description

Statement

Reference

Expression of Antp^Scer\UAS.cMa under the control of Scer\GAL4^arm.PS transforms the T1 segment towards a T2 fate in the larval cuticle.

(Noro et al., 2011)

15% of the embryonic/first instar larval cuticles of Antp^Scer\UAS.cMa; Scer\GAL4^arm.PS animals lack Keilin's organs.

(Gebelein et al., 2002)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Other

Statement

Reference

Antp^UAS.cMa, Scer\GAL4^arm.PS, abd-A^{ΔC220.UAS.Tag:MYC} has homeotic phenotype

(Noro et al., 2011)

Antp^UAS.cMa, Scer\GAL4^arm.PS, abd-A^UAS.Tag:MYC has homeotic phenotype

(Noro et al., 2011)

Antp^UAS.cMa, Scer\GAL4^arm.PS, abd-A^{W1+2A.UAS.Tag:MYC} has homeotic phenotype

(Noro et al., 2011)

Antp^UAS.cMa, Scer\GAL4^arm.PS, abd-A^{ΔC263.UAS.Tag:MYC} has homeotic phenotype

(Noro et al., 2011)

Phenotype Manifest In

Other

Statement

Reference

Antp^UAS.cMa, Scer\GAL4^arm.PS, abd-A^UAS.Tag:MYC has larval prothoracic segment phenotype

(Noro et al., 2011)

Antp^UAS.cMa, Scer\GAL4^arm.PS, abd-A^UAS.Tag:MYC has larval abdominal segment 2 | ectopic phenotype

(Noro et al., 2011)

Antp^UAS.cMa, Scer\GAL4^arm.PS, abd-A^{ΔC220.UAS.Tag:MYC} has larval abdominal segment 2 | ectopic phenotype

(Noro et al., 2011)

Antp^UAS.cMa, Scer\GAL4^arm.PS, abd-A^{W1+2A.UAS.Tag:MYC} has larval prothoracic segment phenotype

(Noro et al., 2011)

Antp^UAS.cMa, Scer\GAL4^arm.PS, abd-A^{W1+2A.UAS.Tag:MYC} has larval abdominal segment 2 | ectopic phenotype

(Noro et al., 2011)

Antp^UAS.cMa, Scer\GAL4^arm.PS, abd-A^{ΔC263.UAS.Tag:MYC} has larval prothoracic segment phenotype

(Noro et al., 2011)

Antp^UAS.cMa, Scer\GAL4^arm.PS, abd-A^{ΔC263.UAS.Tag:MYC} has larval abdominal segment 2 | ectopic phenotype

(Noro et al., 2011)

Antp^UAS.cMa, Scer\GAL4^arm.PS, abd-A^{ΔC220.UAS.Tag:MYC} has larval prothoracic segment phenotype

(Noro et al., 2011)

Additional Comments

Genetic Interactions

Statement

Reference

Larvae co-expressing abd-A^{Scer\UAS.T:Hsap\MYC} and Antp^Scer\UAS.cMa under the control of Scer\GAL4^arm.PS show transformation of the T1 segment towards an A2 fate (as occurs when abd-A^{Scer\UAS.T:Hsap\MYC} is expressed alone).

Larvae co-expressing abd-A^{W1+2A.Scer\UAS.T:Hsap\MYC} and Antp^Scer\UAS.cMa under the control of Scer\GAL4^arm.PS show transformation of the T1 segment towards an A2 fate.

Larvae co-expressing abd-A^{ΔC263.Scer\UAS.T:Hsap\MYC} and Antp^Scer\UAS.cMa under the control of Scer\GAL4^arm.PS show transformation of the T1 segment towards an A2 fate.

Larvae co-expressing abd-A^{ΔC220.Scer\UAS.T:Hsap\MYC} and Antp^Scer\UAS.cMa under the control of Scer\GAL4^arm.PS show transformation of the T1 segment towards an A2 fate.

Only 40% of larvae co-expressing abd-A^{Δ200-220.Scer\UAS.T:Hsap\MYC} and Antp^Scer\UAS.cMa under the control of Scer\GAL4^arm.PS show transformation of the T1 segment towards an A2 fate.

Only 2% of larvae co-expressing abd-A^{2WAla.Δ200-220.Scer\UAS.T:Hsap\MYC} and Antp^Scer\UAS.cMa under the control of Scer\GAL4^arm.PS show transformation of the T1 segment towards an A2 fate.

Only 11% of larvae co-expressing abd-A^{ΔC197.Scer\UAS.T:Hsap\MYC} and Antp^Scer\UAS.cMa under the control of Scer\GAL4^arm.PS show transformation of the T1 segment towards an A2 fate.

(Noro et al., 2011)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Antp^Scer\UAS.cMa

Antp^UAS.cMa

Name Synonyms

Saccharomyces cerevisiae UAS construct a of Moreno

(Azpiazu and Morata, 1998)

Secondary FlyBase IDs

References (7)

Report Sections

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