FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\wgGMR.PW
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General Information
Symbol
Dmel\wgGMR.PW
Species
D. melanogaster
Name
glass multimer reporter construct of Wehrli
FlyBase ID
FBal0090042
Feature type
allele
Associated gene
Dmel\wg
Associated Insertion(s)
Carried in Construct
P{GMR-wg.W}
Also Known As
GMR-wg
Key Links
Transgenic product class
wild_type
(Wehrli and Tomlinson, 1998)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Wehrli and Tomlinson, 1998)
Mutagen
in vitro construct
(Wehrli and Tomlinson, 1998)
Progenitor genotype
Carried in construct
P{GMR-wg.W}
Cytology
Description

wg is expressed under the control of the GMR enhancer.

(Wehrli and Tomlinson, 1998)
Allele components
Component
Use(s)
Regulatory region(s)
GMR
Encoded product / tool
wg
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of wgGMR.PW results in small, heavily pigmented eyes.

      (Lim and Tomlinson, 2006)

      Expression of wgGMR.PW at high levels in the developing retina causes the eye to be unusually small and to consist almost entirely of pigment rim-like cells. Additionally, necrotic regions are observed amongst these cells. Eyes become smaller in proportion to the number of copies of wgGMR.PW expressed.

      (Tomlinson, 2003)

      Flies expressing wgGMR.PW have very small eyes consisting almost entirely of pigment cells.

      (Wehrli and Tomlinson, 1998)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressed by
      Statement
      Reference

      wgGMR.PW has visible phenotype, suppressible by arr2

      (Wehrli and Tomlinson, 1998)
      Phenotype Manifest In
      Suppressed by
      Statement
      Reference

      wgGMR.PW has ommatidium phenotype, suppressible by arr2

      (Wehrli and Tomlinson, 1998)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      arr2 clones induced in eyes expressing wgGMR.PW show an autonomous rescue of ommatidia.

      (Wehrli and Tomlinson, 1998)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      wgGMR.PW
      Name Synonyms
      glass multimer reporter construct of Wehrli
      (Wehrli and Tomlinson, 1998)
      Secondary FlyBase IDs
        References (3)