FlyBase Allele Report: Dmel\tkv[SC143]

General Information

Symbol

Dmel\tkv^SC143

Species

D. melanogaster

Name

FlyBase ID

FBal0090088

Feature type

allele

Associated gene

Dmel\tkv

Associated Insertion(s)

P{UAS-tkv.Q199D.C}SC143

Carried in Construct

Key Links

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Das and Cho, 1998.6.17)

Progenitor genotype

tkv^Q199D.UAS

(Das and Cho, 1998.6.17)

Associated Insertion(s)

P{UAS-tkv.Q199D.C}SC143

Cytology

Description

Encodes a constitutively active form of tkv.

(Das et al., 1998)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible

(Das et al., 1998)

Phenotype Manifest In

wing

(Das et al., 1998)

wing vein | ectopic

(Das et al., 1998)

Detailed Description

Statement

Reference

tkv^SC143 flies have wing defects, such as ectopic venation and severe blistering.

(Das et al., 1998)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

tkv^SC143 has visible phenotype, suppressible by Mad[+]/Mad¹⁰

(Das et al., 1998)

tkv^SC143 has visible phenotype, suppressible by Mad¹²/Mad[+]

(Das et al., 1998)

tkv^SC143 has visible phenotype, suppressible by Med[+]/Med¹

(Das et al., 1998)

tkv^SC143 has visible phenotype, suppressible by Med[+]/Med²⁷

(Das et al., 1998)

tkv^SC143 has visible phenotype, suppressible by Med[+]/Med²³

(Das et al., 1998)

tkv^SC143 has visible phenotype, suppressible by Med²⁶/Med[+]

(Das et al., 1998)

Phenotype Manifest In

Suppressed by

Statement

Reference

tkv^SC143 has wing phenotype, suppressible by Med[+]/Med¹

(Das et al., 1998)

tkv^SC143 has wing phenotype, suppressible by Med[+]/Med²⁷

(Das et al., 1998)

tkv^SC143 has wing phenotype, suppressible by Med[+]/Med²³

(Das et al., 1998)

tkv^SC143 has wing phenotype, suppressible by Med²⁶/Med[+]

(Das et al., 1998)

tkv^SC143 has wing phenotype, suppressible by Mad[+]/Mad¹⁰

(Das et al., 1998)

tkv^SC143 has wing vein | ectopic phenotype, suppressible by Mad[+]/Mad¹⁰

(Das et al., 1998)

tkv^SC143 has wing phenotype, suppressible by Mad¹²/Mad[+]

(Das et al., 1998)

tkv^SC143 has wing vein | ectopic phenotype, suppressible by Mad¹²/Mad[+]

(Das et al., 1998)

Additional Comments

Genetic Interactions

Statement

Reference

The tkv^SC143 wing phenotype is suppressed by one copy of Mad¹⁰, Mad¹², but one copy of Med¹, Med²⁷, Med²³ or Med²⁶ results in only a slight decrease in blistering.

(Das et al., 1998)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

S.H. Cho

(Das and Cho, 1998.6.17)

Comments

Enhancer piracy line.

(Das and Cho, 1998.6.17)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Tkv^*

(Das et al., 1998)

tkv^SC143

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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