FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\MedD5
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General Information
Symbol
Dmel\MedD5
Species
D. melanogaster
Name
FlyBase ID
FBal0090581
Feature type
allele
Associated gene
Dmel\Med
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl nitrosourea
(Chen et al., 1998)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Lethal in transheterozygous combination with Med4.

      (Chen et al., 1998)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Other
      Statement
      Reference

      MedD5, tkv6 has visible | dominant phenotype

      (Chen et al., 1998)

      Df(2L)tkv2, MedD5 has visible | dominant phenotype

      (Chen et al., 1998)

      MedD5, tkv6 has visible | recessive phenotype

      (Chen et al., 1998)
      Phenotype Manifest In
      Other
      Statement
      Reference

      MedD5, tkv6 has scutum phenotype

      (Chen et al., 1998)

      MedD5, tkv6 has leg phenotype

      (Chen et al., 1998)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      MedD5 dominantly enhances the tkv6 phenotype; tkv6 homozygotes have a normal notum and legs, but the presence of one copy of MedD5 results in defects in the notum and legs. Double heterozygotes with Df(2L)tkv2 may show imaginal disc development defects. No interaction with put135 is seen in double heterozygous flies.

      (Chen et al., 1998)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Selected as: Dominant enhancer of the tkv6 phenotype.

      (Chen et al., 1998)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      D5
      (Chen et al., 1998)
      MedD5
      Name Synonyms
      Secondary FlyBase IDs
        References (1)