FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\vas6356-005
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General Information
Symbol
Dmel\vas6356-005
Species
D. melanogaster
Name
FlyBase ID
FBal0091101
Feature type
allele
Associated gene
Dmel\vas
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Tinker et al., 1998)
Progenitor genotype
Cytology
Description

Amino acid replacement: T546S.

(Tinker et al., 1998)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
2L:15,073,678..15,073,678 [+]
Nucleotide change:

A15073678T

Amino acid change:

T546S | vas-PA; T546S | vas-PB; T546S | vas-PC

Reported amino acid change:

T546S

Comment:

Amino acid replacement reported as reported as Thr to Ser, which could result from a nucleotide substitution in the first or second base of the codon. The mutation was annotated at the first base of the codon.

(Tinker et al., 1998)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous vas6356-005, vas6356-001/vas6356-005 and vas6356-005/Df(2L)b87e25 females are sterile.

      (Tinker et al., 1998)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      vas6356-001/vas6356-005 does not alter the dorsalised eggshell phenotype of eggs derived from fs(1)K10unspecified females.

      (Tinker et al., 1998)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      6356-005
      (Yan et al., 2010)
      cgt6356-005
      fs(2)6356005
      (Tinker et al., 1998)
      vas6356-005
      Name Synonyms
      Secondary FlyBase IDs
        References (2)