FB2026_02 , released June 18, 2026
Allele: Dmel\Hr3856
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General Information
Symbol
Dmel\Hr3856
Species
D. melanogaster
Name
FlyBase ID
FBal0091744
Feature type
allele
Associated gene
Dmel\Hr38
Associated Insertion(s)
Carried in Construct
Also Known As
Dhr3856
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Kozlova et al., 1998)
Progenitor genotype
Cytology
Description

This lesion affects the coding sequences of both Hr38 mRNA isoforms.

(Kozlova et al., 2009)

Amino acid replacement: Y607term.

(Kozlova et al., 2009)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
2L:20,688,528..20,688,528 [-]
Nucleotide change:

T20688528R

Amino acid change:

Y607term | Hr38-PB; Y365term | Hr38-PD

Reported amino acid change:

Y607term

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

(Kozlova et al., 2009)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Two thirds of hemizygotes develop normally to the late pupal stage and pharate adults look externally normal when dissected. However cuticle ruptures when the pharate flies start moving before eclosion.

      (Kozlova et al., 1998)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      Hr3802306

      (Kozlova et al., 1998)
      Partially rescued by

      Hr3856 is partially rescued by Hr38hs.11

      (Kozlova et al., 1998)

      Hr3856 is partially rescued by Hr38hs.61

      (Kozlova et al., 1998)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      DHR3856
      (Kozlova et al., 2009)
      Dhr3856
      (Davis et al., 2007)
      Hr3856
      Name Synonyms
      Secondary FlyBase IDs
        References (3)