FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\tin::MmusNkx2-52.5HD-NK2SD.hs
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General Information
Symbol
Dmel\tin::Mmus\Nkx2-52.5HD-NK2SD.hs
Species
D. melanogaster
Name
FlyBase ID
FBal0092499
Feature type
allele
Associated gene
tin::Mmus\Nkx2-5
Associated Insertion(s)
Carried in Construct
P{tin:2.5HD-NK2SD}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Park et al., 1998)
Progenitor genotype
Carried in construct
P{tin:2.5HD-NK2SD}
Cytology
Description

A chimeric construct in which the tin homeodomain has been replaced by the Mmus\Nkx2-5 homeodomain and NK2-specific domain is expressed under the control of an Hsp70 promoter.

(Park et al., 1998)
Allele components
Component
Use(s)
Regulatory region(s)
Hsp70
Encoded product / tool
tin::Mmus\Nkx2-5
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      tin::Mmus\Nkx2-52.5HD-NK2SD.hs is a suppressor of larval pericardial cell phenotype of tinEC40

      (Park et al., 1998)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Restores the formation of pericardial cells when expressed in tinEC40 embryos at 3.5 to 4.5 hours of development, although the cells are in a disorganised pattern.

      (Park et al., 1998)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Assayed in D.melanogaster.

      (Park et al., 1998)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      tin::Mmus\Nkx2-52.5HD-NK2SD.hs
      Name Synonyms
      Secondary FlyBase IDs
        References (1)