FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\okrAO
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General Information
Symbol
Dmel\okrAO
Species
D. melanogaster
Name
FlyBase ID
FBal0092588
Feature type
allele
Associated gene
Dmel\okr
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

antimorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

antimorphic allele - genetic evidence

(Ghabrial et al., 1998)
Mutagen
ethyl methanesulfonate
(Ghabrial et al., 1998)
Progenitor genotype
Cytology
Description

Amino acid replacement: A601V.

(Ghabrial et al., 1998)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
2L:2,990,737..2,990,737 [-]
Nucleotide change:

C2990737T

Amino acid change:

A601V | okr-PA

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

(Ghabrial et al., 1998)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Hemizygotes are viable. Homozygous and hemizygous females are fertile, showing 25% and 50% hatching rates respectively. Recombination frequency is 50% of normal levels in homozygous females, and X chromosome non-disjunction is increased 17- to 20-fold compared to wild-type. Recombination frequency is 50% of normal levels in okrAA/okrAO females.

      (Ghabrial et al., 1998)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      okrWS

      (Ghabrial et al., 1998)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      okrAO
      Name Synonyms
      Secondary FlyBase IDs
        References (1)