FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dvir\sisAsisA.PK
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General Information
Symbol
Dvir\sisAsisA.PK
Species
D. virilis
Name
sisterless A promoter construct of Erickson
FlyBase ID
FBal0093420
Feature type
allele
Associated gene
Dvir\sisA
Associated Insertion(s)
Carried in Construct
P{SISA-VIR.K}
Transgenic product class
wild_type
(Erickson and Cline, 1998)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Erickson and Cline, 1998)
Mutagen
in vitro construct
(Erickson and Cline, 1998)
Progenitor genotype
sisA+t6.4
(Erickson and Cline, 1998)
Carried in construct
P{SISA-VIR.K}
Cytology
Description

The D. melanogaster sisA coding region and 31bp of 3' sequence have been replaced by the Dvir\sisA coding region and 14bp of 3' sequence.

(Erickson and Cline, 1998)
Allele components
Component
Use(s)
Regulatory region(s)
sisA
Encoded product / tool
Dvir\sisA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Other
      Statement
      Reference

      Dvir\sisAsisA.PK, sisA1 has viable phenotype

      (Erickson and Cline, 1998)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      A single copy fully rescues D.melanogaster females homozygous for sisA1, but only partially rescues females hemizygous for sisA1. Also shows activity in males, revealed as a male-specific lethal effect in combination with a duplication for 'sisB' i.e. sc.

      (Erickson and Cline, 1998)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Dvir\sisAsisA.PK
      Name Synonyms
      sisterless A promoter construct of Erickson
      (Erickson and Cline, 1998)
      Secondary FlyBase IDs
        References (1)