FB2026_02 , released June 18, 2026
Allele: Dmel\DabΔPro.hs.2sev
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General Information
Symbol
Dmel\DabΔPro.hs.2sev
Species
D. melanogaster
Name
FlyBase ID
FBal0093450
Feature type
allele
Associated gene
Dmel\Dab
Associated Insertion(s)
Carried in Construct
P{sE-dabΔPro}
Key Links
Transgenic product class
wild_type
(Le and Simon, 1998)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Le and Simon, 1998)
Mutagen
in vitro construct
(Le and Simon, 1998)
Progenitor genotype
Dabhs.2sev
(Le and Simon, 1998)
Carried in construct
P{sE-dabΔPro}
Cytology
Description

Deletion of the proline-rich region.

(Le and Simon, 1998)
Allele components
Component
Use(s)
Regulatory region(s)
Hsp70
sev
Encoded product / tool
Dab
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Has no effect on eye development when expressed in a wild-type background.

      (Le and Simon, 1998)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      DabΔPro.hs.2sev is an enhancer of visible | dominant phenotype of sevS11.Tag:MYC

      (Le and Simon, 1998)
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      DabΔPro.hs.2sev is an enhancer of eye phenotype of sevS11.Tag:MYC

      (Le and Simon, 1998)

      DabΔPro.hs.2sev is an enhancer of photoreceptor cell R7 | ectopic phenotype of sevS11.Tag:MYC

      (Le and Simon, 1998)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Enhances the rough eye phenotype of sevS11.T:Hsap\MYC flies. Reverses the suppressor effect of Nrtunspecified on the rough eye and extra R7 photoreceptor cell phenotype of sevS11.T:Hsap\MYC flies.

      (Le and Simon, 1998)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      DabΔPro.hs.2sev
      Name Synonyms
      Secondary FlyBase IDs
        References (1)