FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\kl-361
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General Information
Symbol
Dmel\kl-361
Species
D. melanogaster
Name
FlyBase ID
FBal0093955
Feature type
allele
Associated gene
Dmel\kl-3
Associated Insertion(s)
P{PZ}kl-361
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
Delta2-3 transposase
(Zhang and Stankiewicz, 1998)
Progenitor genotype
P{PZ}Y95-2
(Zhang and Stankiewicz, 1998)
Associated Insertion(s)
P{PZ}kl-361
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{PZ}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Normal looking individualisation complexes (ICs) are seen in the testes of X/kl-361 males. Spermatid tails show irregularities.

      (Timakov and Zhang, 2000)

      Male sterile in combination with Ts(1Lt;YSt)W27, Ts(1Lt;YSt)E15 or Ts(1Lt;YSt)F12. Male fertile in combination with Ts(1Lt;YSt)V24, Ts(1Lt;YLt)V8 or Ts(1Lt;YLt)W19. kl-361 testes show degradation in the basal testicular region. Sperm are absent from the seminal vesicles. Postmeiotic nuclei show almost normal nuclear condensation, except for the appearance of occasional singular needle-shaped nuclear heads. The organised bundles of the elongated sperm heads are eventually disintegrated in the basal region of the testis before the spermatids reach maturity. Defects are seen in the flagellar axoneme; the outer arm dyneins are lost of greatly reduced.

      (Zhang and Stankiewicz, 1998)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Male sterile phenotype can be reverted in the presence of a transposase source.

      (Zhang and Stankiewicz, 1998)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      kl-361
      ms(Y)104b61
      ms(Y)61
      (Zhang and Stankiewicz, 1998)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)