FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\alex
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General Information
Symbol
Dmel\alex
Species
D. melanogaster
Name
FlyBase ID
FBal0094587
Feature type
allele
Associated gene
Dmel\al
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Campbell and Tomlinson, 1998)
Progenitor genotype
alX21
(Campbell and Tomlinson, 1998)
Cytology
Description

Precise excision of the P{lacW} element.

(Campbell and Tomlinson, 1998)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      alice/alex flies are missing claws, the arista in the antenna and medial notum bristles.

      (Kojima et al., 2005)

      All pretarsus structures in the leg and the arista are lost in alex/alice flies.

      (Tsuji et al., 2000)

      Homozygotes die as embryos with no obvious phenotype. al1/alex flies show loss of the arista. The only clear phenotype associated with homozygous clones in the wing is a deletion of part of vein II. The only region of the leg affected by homozygous clones is the tip of the leg where the claw organ is completely deleted amd the last two tarsal segments are deleted in size. Clones must be present in both anterior and posterior compartments to delete both claws. Homozygous clones in the sternopleurum and scutellum show extreme al mutant phenotypes.

      (Campbell and Tomlinson, 1998)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescued by

      alex is partially rescued by alB38

      (Campbell and Tomlinson, 1998)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      alex
      (Martín et al., 2017, Emmons et al., 2007, Tajiri et al., 2007)
      Name Synonyms
      Secondary FlyBase IDs
        References (7)