FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Su(H)UAS.Tag:MYC
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General Information
Symbol
Dmel\Su(H)UAS.Tag:MYC
Species
D. melanogaster
Name
FlyBase ID
FBal0094607
Feature type
allele
Associated gene
Dmel\Su(H)
Associated Insertion(s)
Carried in Construct
P{UAS-Su(H).myc}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Kidd et al., 1998)
Progenitor genotype
Carried in construct
P{UAS-Su(H).myc}
Cytology
Description

The first 2 amino acids of cact followed by Tag:MYC is fused to amino acid 10 of Su(H) coding region.

(Kidd et al., 1998)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Su(H)
Tagged with
Tag:MYC
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      ameliorates  autosomal dominant cerebellar ataxia
      modeled by Hsap\TBP80Q.UAS
      (Ren et al., 2011)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of Su(H)Scer\UAS.T:Hsap\MYC under the control of Scer\GAL4ato.3.6 strongly reduces the number of medulla axons in the adult brain compared to wild type

      (Langen et al., 2013)

      Expression of Su(H)Scer\UAS.T:Hsap\MYC under the control of Scer\GAL4insc-Mz1407 does not result in a significant change in the number of type II central brain neuroblasts compared to wild type.

      Expression of Su(H)Scer\UAS.T:Hsap\MYC under the control of Scer\GAL4GMR9D11 does not result in an increase in the number of brain neuroblasts compared to wild type.

      (Lee et al., 2013)

      Expression of Su(H)Scer\UAS.T:Hsap\MYC under the control of Scer\GAL4Eq1 results in a substantial balding phenotype on the notum.

      (Duan et al., 2011)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhanced by
      Statement
      Reference

      Scer\GAL4Eq, Su(H)UAS.Tag:MYC has visible phenotype, enhanceable by insvunspecified

      (Duan et al., 2011)
      Suppressor of
      Statement
      Reference

      Su(H)UAS.Tag:MYC, Scer\GAL4GMR.PU is a suppressor | partially of visible phenotype of Hsap\TBP80Q.UAS, Scer\GAL4GMR.PU

      (Ren et al., 2011)
      Phenotype Manifest In
      Enhanced by
      Statement
      Reference

      Scer\GAL4Eq, Su(H)UAS.Tag:MYC has chaeta phenotype, enhanceable by insvunspecified

      (Duan et al., 2011)
      Suppressor of
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of Su(H)Scer\UAS.T:Hsap\MYC and Akt1S505D.Scer\UAS under the control of Scer\GAL4GMR9D11 results in an increase in the number of brain neuroblasts compared to wild type.

      (Lee et al., 2013)

      insvunspecified enhances the notum balding phenotype caused by expression of Su(H)Scer\UAS.T:Hsap\MYC under the control of Scer\GAL4Eq1.

      (Duan et al., 2011)
      Xenogenetic Interactions
      Statement
      Reference

      Overexpression of Su(H)Scer\UAS.T:Hsap\MYC under the control of Scer\GAL4GMR.PU partially suppresses the eye abnormalities caused by the overexpression of Hsap\TBP80Q.Scer\UAS with an improvement in both the shape and organisation of ommatidia. Ommatidial fusion is no longer observed and pigment loss is less severe.

      (Ren et al., 2011)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Carried in plasmid and used in S2 cells as well as transgenic Drosophila.

      (Kidd et al., 1998)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Su(H)Scer\UAS.T:Hsap\MYC
      Su(H)UAS.T:Myc
      Su(H)UAS.Tag:MYC
      Name Synonyms
      Secondary FlyBase IDs
        References (6)