FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\hook7
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General Information
Symbol
Dmel\hook7
Species
D. melanogaster
Name
FlyBase ID
FBal0095357
Feature type
allele
Associated gene
Dmel\hook
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl nitrosourea
(Kramer and Phistry, 1999)
Progenitor genotype
Cytology
Description

Nucleotide substitution stated to be C2014T, but 2014 is a typographical error (corrected, see Kramer, 1999.12.2, personal communication). Amino acid replacement: ?185@.

(Kramer and Phistry, 1999)

Nucleotide substitution: C1014T.

(Kramer, 1999.12.2)

Amino acid replacement: ?186term.

(Kramer, 1999.12.2)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
2L:19,032,770..19,032,770 [-]
Nucleotide change:

C19032770T

Amino acid change:

Q186term | hook-PA

Comment:

Results in a 185aa polypeptide.

(Kramer and Phistry, 1999)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Hemizygotes have a hooked-bristle phenotype.

      (Kramer and Phistry, 1999)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      hook1

      (Kramer and Phistry, 1999)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Selected as: a mutation that fails to complement hk1.

      (Kramer and Phistry, 1999)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      hk7
      hook7
      (Lu et al., 2020)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)