FB2026_02 , released June 18, 2026
Allele: Dmel\DrefCR3.UAS
Open Close
General Information
Symbol
Dmel\DrefCR3.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0095817
Feature type
allele
Associated gene
Dmel\Dref
Associated Insertion(s)
Carried in Construct
P{UAS-Dref.CR3}
Key Links
Transgenic product class
inframe_deletion
(Takahashi et al., 1999)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Takahashi et al., 1999)
Mutagen
in vitro construct
(Takahashi et al., 1999)
Progenitor genotype
Carried in construct
P{UAS-Dref.CR3}
Cytology
Description

Amino acids 604-704 of Dref are expressed from UASt regulatory sequences.

(Takahashi et al., 1999)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Dref
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      When expression is driven by Scer\GAL4GMR.PS the eyes are roughened. Ommatidia and interommatidial bristles are irregular. Two copies of DrefCR3.Scer\UAS cause ommatidia to fuse. The phenotype is more pronounced than for DrefCR1.Scer\UAS. Examination of BrdU incorporation indicates the S phase zone for the second mitotic wave posterior to the morphogenetic furrow is reduced.

      (Takahashi et al., 1999)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      DrefCR3.Scer\UAS
      DrefCR3.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (1)