FlyBase Allele Report: Dmel\Tlk[G0054]

General Information

Symbol

Dmel\Tlk^G0054

Species

D. melanogaster

Name

FlyBase ID

FBal0096844

Feature type

allele

Associated gene

Dmel\Tlk

Associated Insertion(s)

P{lacW}Tlk^G0054

Carried in Construct

Also Known As

tlk^l(1)G0054

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Schäfer et al., 1999.3.29)

Progenitor genotype

Associated Insertion(s)

P{lacW}Tlk^G0054

Cytology

Description

The P{lacW} insertion is within the first intron of the tlk gene.

(Carrera et al., 2003)

Allele components

Component

Use(s)

Inserted element

P{lacW}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

X:3,781,167..3,781,938 [+]

(Carrera et al., 2003, Peter et al., 2002, Schäfer et al., 1999.3.29, Schäfer et al., 1999.6.15)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

AJ300099

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | germline clone | male limited

(Carrera et al., 2003)

lethal | larval stage

(Peter et al., 2002)

lethal | larval stage | recessive

(Carrera et al., 2003)

lethal | prepupal stage

(Peter et al., 2002)

lethal | pupal stage

(Peter et al., 2002)

lethal | recessive

(Schäfer et al., 1999.3.29)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

11593

w^67c23 P{lacW}Tlk^G0054/FM7c, sn⁺

Kyoto

111773

w^67c23 P{lacW}Tlk^G0054 P{neoFRT}19A/FM7c; P{ey-FLP.N}5

Notes on Origin

Discoverer

Comments

P{lacW} not verified as causing the lethality.

(Schäfer et al., 1999.3.29)

Precise excision of the P{lacW} element fully restores viability.

(Carrera et al., 2003)

External Crossreferences and Linkouts ( 1 )

Crossreferences

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

AJ300099

Synonyms and Secondary IDs (5)

Reported As

Symbol Synonym

Tlk^G0054

l(1)G0054

(Peter et al., 2002)

l(1)G0054^G0054

(Schäfer et al., 1999.3.29, Schäfer et al., 1999.6.15)

tlk^G0054

tlk^l(1)G0054

(Zhang et al., 2016, Carrera et al., 2003)

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections

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