FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Btau\MAPTUAS.cTa
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General Information
Symbol
Btau\MAPTUAS.cTa
Species
B. taurus
Name
Saccharomyces cerevisiae UAS construct a of Torroja
FlyBase ID
FBal0097392
Feature type
allele
Associated gene
Btau\MAPT
Associated Insertion(s)
Carried in Construct
P{UAS-tau.T}
Transgenic product class
wild_type
(Torroja et al., 1999)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Torroja et al., 1999)
Mutagen
in vitro construct
(Torroja et al., 1999)
Progenitor genotype
Carried in construct
P{UAS-tau.T}
Cytology
Description

Expression of a Btau\MAPT coding region is governed by UAS regulatory sequences.

(Torroja et al., 1999)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Btau\MAPT
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Either Btau\MAPTScer\UAS.cTa or ApplScer\UAS.cTa alone, when driven by Scer\GAL4Appl.G1a, cause 67% viability. The inviable flies do not show the infantile phenotype, in general. Similar phenotypes occur with the Scer\GAL4elav-C155 driver.

      (Torroja et al., 1999)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      37.9% viability when Btau\MAPTScer\UAS.cTa is driven by Scer\GAL4Appl.G1a in combination with ApplScer\UAS.cTa. In all cases lethality acts mostly during the pharate adult stage. Eclosing adults show an infantile phenotype where wing expansion and cuticle hardening did not occur. Transport of axonal cargo is reduced in the Btau\MAPTScer\UAS.cTa, ApplScer\UAS.cTa double mutant.

      (Torroja et al., 1999)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Btau\MAPTScer\UAS.cTa
      Btau\MAPTUAS.cTa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Torroja
      (Torroja et al., 1999)
      Secondary FlyBase IDs
        References (1)