FlyBase Allele Report: Dmel\Actn[G0077]

General Information

Symbol

Dmel\Actn^G0077

Species

D. melanogaster

Name

FlyBase ID

FBal0097427

Feature type

allele

Associated gene

Dmel\Actn

Associated Insertion(s)

P{lacW}Actn^G0077

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Schäfer et al., 1999.3.29)

Progenitor genotype

Associated Insertion(s)

P{lacW}Actn^G0077

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{lacW}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

X:2,032,517..2,033,244 [-]

(Peter et al., 2002, Benos et al., 2001, Schäfer et al., 1999.3.29, Schäfer et al., 1999.6.15)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

AJ300034

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | larval stage

(Peter et al., 2002)

lethal | prepupal stage

(Peter et al., 2002)

lethal | pupal stage

(Peter et al., 2002)

lethal | recessive

(Schäfer et al., 1999.3.29)

Phenotype Manifest In

Detailed Description

Statement

Reference

Lethality occurs from the third larval instar through to the pupal stage.

(Peter et al., 2002)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Other

Statement

Reference

Actn^G0077, vri^5R7.2/vri[+] has visible | dominant phenotype

(Szuplewski et al., 2003)

Actn^G0077, vri[+]/vri^unspecified has abnormal locomotor behavior | dominant phenotype

(Szuplewski et al., 2003)

Actn[+]/Actn^G0077, vri^5R7.2 has visible phenotype

(Szuplewski et al., 2003)

Actn[+]/Actn^G0077, vri^unspecified has abnormal locomotor behavior phenotype

(Szuplewski et al., 2003)

Phenotype Manifest In

Other

Statement

Reference

Actn^G0077, vri^5R7.2 has wing hair phenotype

(Szuplewski et al., 2003)

Actn^G0077, vri^5R7.2 has wing margin | anterior phenotype

(Szuplewski et al., 2003)

Actn^G0077, vri^unspecified has metathoracic leg phenotype

(Szuplewski et al., 2003)

Additional Comments

Genetic Interactions

Statement

Reference

Actn^G0077 vri^unspecified double heterozygotes have progressive locomotory defects affecting the rear legs. vri^5R7.2 Actn^G0077 double heterozygotes have missing hairs at the anterior wing margin and on the wing surface.

(Szuplewski et al., 2003)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

P{lacW} verified as causing the lethality.

(Schäfer et al., 1999.3.29)

External Crossreferences and Linkouts ( 1 )

Crossreferences

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

AJ300034

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Actn^G0077

l(1)G0077

(Peter et al., 2002, Benos et al., 2001)

Name Synonyms

Secondary FlyBase IDs

References (6)

Report Sections

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