FB2026_02 , released June 18, 2026
Allele: Dmel\mei-41A2
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General Information
Symbol
Dmel\mei-41A2
Species
D. melanogaster
Name
FlyBase ID
FBal0097959
Feature type
allele
Associated gene
Dmel\mei-41
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Smith, 1976)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      mei-41A2 mutants have a reduced frequency of single-strand annealing repair (SSA) compared to controls in a P{wIw.FRT} hemizygous assay to study DNA double-stranded break repair when assayed at 38oC.

      (Wei and Rong, 2007)

      Hemizygous male larvae are sensitive to methyl methanesulfonate (MMS). Sensitivity to MMS is recessive at 0.075% MMS and shows a strong semidominant effect at 0.125% MMS. Only 8.0% of eggs laid by homozygous females develop into adults that eclose.

      (Smith, 1976)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      mei-41A1

      (Smith, 1976)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Fails to complement: mus102A1.

      (Smith, 1976)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      mei-41A2
      (Wei and Rong, 2007)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)