FlyBase Allele Report: Dmel\pck[G0044]

General Information

Symbol

Dmel\pck^G0044

Species

D. melanogaster

Name

FlyBase ID

FBal0098216

Feature type

allele

Associated gene

Dmel\pck

Associated Insertion(s)

P{lacW}pck^G0044

Carried in Construct

Also Known As

mega^G0044

Key Links

Genomic Maps

JBrowse

Allele class

amorphic allele - genetic evidence

Mutagen

P-element activity

Nature of the Allele

Allele class

amorphic allele - genetic evidence

(Behr et al., 2003)

Mutagen

P-element activity

(Schäfer et al., 1999.6.15, Schäfer et al., 1999.8.12)

Progenitor genotype

Associated Insertion(s)

P{lacW}pck^G0044

Cytology

Description

Insertion of P{lacW} into the 5' untranslated region of pck, 83bp upstream of the putative translation start site, in reverse orientation.

(Behr et al., 2003)

Allele components

Component

Use(s)

Inserted element

P{lacW}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

X:1,470,320..1,470,903 [-]

(Harder et al., 2008, Wu et al., 2004, Behr et al., 2003, Peter et al., 2002, Schäfer et al., 1999.6.15, Schäfer et al., 1999.8.12)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

AJ300013

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Schäfer et al., 1999.6.15, Schäfer et al., 1999.8.12)

lethal - all die during embryonic stage

(Peter et al., 2002)

some die during embryonic stage

(Peter et al., 2002)

Phenotype Manifest In

tracheal dorsal trunk primordium

(Behr et al., 2003)

tracheal transverse connective primordium

(Behr et al., 2003)

Detailed Description

Statement

Reference

Elongated and tortuous tracheal branches, most prominantly in the dorsal trunk.

(Behr et al., 2003)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

pck^VE896

(Behr et al., 2003)

pck^EA97

(Behr et al., 2003)

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Kyoto

111769

y¹ P{lacW}pck^G0044 w^* P{neoFRT}19A/FM7c; P{ey-FLP.N}5

Notes on Origin

Discoverer

Comments

P{lacW} not verified as causing the lethality.

(Schäfer et al., 1999.6.15, Schäfer et al., 1999.8.12)

External Crossreferences and Linkouts ( 1 )

Crossreferences

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

AJ300013

Synonyms and Secondary IDs (6)

Reported As

Symbol Synonym

l(1)G0012^G0044

l(1)G0044

(Peter et al., 2002)

l(1)G0044^G0044

(Schäfer et al., 1999.6.15, Schäfer et al., 1999.8.12)

mega⁴⁴

(Harder et al., 2008)

mega^G0044

(Wu et al., 2004, Behr et al., 2003)

pck^G0044

Name Synonyms

Secondary FlyBase IDs

References (6)

Report Sections

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