FB2026_02 , released June 18, 2026
Allele: Hsap\SLC11A1hs.PD
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General Information
Symbol
Hsap\SLC11A1hs.PD
Species
H. sapiens
Name
heat shock construct of D'Souza
FlyBase ID
FBal0098375
Feature type
allele
Associated gene
Hsap\SLC11A1
Associated Insertion(s)
Carried in Construct
P{hs-Hsap\NRAMP1.D}
Key Links
Transgenic product class
wild_type
(D'Souza et al., 1999)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(D'Souza et al., 1999)
Mutagen
in vitro construct
(D'Souza et al., 1999)
Progenitor genotype
Carried in construct
P{hs-Hsap\NRAMP1.D}
Cytology
Description

An Hsp70 promoter drives expression of the complete open reading frame of Hsap\SLC11A1.

(D'Souza et al., 1999)
Allele components
Component
Use(s)
Regulatory region(s)
Hsp70
Encoded product / tool
Hsap\SLC11A1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Flies in which Hsap\NRAMP1hs.PD is expressed using heat shock at 37oC for 1 hour at different times during development show no morphological defects. Flies carring Hsap\NRAMP1hs.PD and reared at 25oC or 27oC show wild-type responses in a feeding preference assay.

      (D'Souza et al., 1999)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      Hsap\SLC11A1hs.PD is a suppressor of abnormal taste perception phenotype of Mvl97f

      (D'Souza et al., 1999)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      Partially rescues the feeding preference assay defects of Mvl97f flies, in a dose-dependent manner.

      (D'Souza et al., 1999)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Hsap\NRAMP1hs.PD
      Hsap\SLC11A1hs.PD
      Name Synonyms
      heat shock construct of D'Souza
      (D'Souza et al., 1999)
      Secondary FlyBase IDs
        References (1)