FB2026_02 , released June 18, 2026
Allele: Dmel\Est-P521S
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General Information
Symbol
Dmel\Est-P521S
Species
D. melanogaster
Name
FlyBase ID
FBal0098395
Feature type
allele
Associated gene
Dmel\Est-P
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
natural population
(Balakirev et al., 2003, Balakirev, 1999.5.13, Balakirev and Ayala, 1996)
Progenitor genotype
Cytology
Description

Nucleotide substitution: T148A.

(Balakirev et al., 2003, Balakirev and Ayala, 1996)

Nucleotide substitutions are numbered from the Est-P start codon and are relative to Est-P255S.

(Balakirev et al., 2003)

Nucleotide substitution: T2218C.

(Balakirev et al., 2003)

Nucleotide substitution: T1451C. Amino acid replacement: Y50N. Amino acid replacement: I153T. Amino acid replacement: I484T. Nucleotide substitutions are numbered from the translation initiation codon and are relative to the Est-P sequence in FBrf0052541. Amino acid residues are numbered according to the Est-P510S nucleotide sequence.

(Balakirev and Ayala, 1996)

Nucleotide substitution: T458C.

(Balakirev and Ayala, 1996)

Nucleotide substitution: A795G.

(Balakirev and Ayala, 1996)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
AF150811
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      El Rio Vineyard, Acampo, Irvine, CA population October 1991.

      (Balakirev, 1999.5.13)

      Isolated from: El Rio Vineyard, Acampo, California, USA population October 1991.

      (Balakirev et al., 2003)

      Isolated from: El Rio Vineyard, Lockeford, California, USA population October 1991.

      (Balakirev and Ayala, 1996)
      External Crossreferences and Linkouts ( 1 )
      Crossreferences
      GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Est-P521S
      S-521S
      (Balakirev et al., 2003)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)