FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Ecol\lacZsal.EME
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General Information
Symbol
Ecol\lacZsal.EME
Species
E. coli
Name
FlyBase ID
FBal0098404
Feature type
allele
Associated gene
Ecol\lacZ
Associated Insertion(s)
Carried in Construct
P{sal-lacZ.EME}
Also Known As
EME
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Barrio et al., 1999, de Celis et al., 1999)
Progenitor genotype
Carried in construct
P{sal-lacZ.EME}
Cytology
Description

1.30kb fragment from a salr intron is fused upstream of lacZ.

(Barrio et al., 1999)

A genomic EcoRI fragment from within the regulatory regions of the spalt complex, within the first salr intron, is placed upstream of a weak P-element promoter followed by sequence encoding nuclear-localized lacZ.

(de Celis et al., 1999)
Allele components
Component
Use(s)
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      late embryonic stage
      embryonic epidermis | restricted
      (Barrio et al., 1999)
      presumptive embryonic/larval peripheral nervous system | restricted
      (Barrio et al., 1999)
      presumptive embryonic/larval central nervous system | restricted
      (Barrio et al., 1999)
      larval stage
      haltere disc | restricted
      (Barrio et al., 1999)
      leg disc | restricted
      (Barrio et al., 1999)
      wing disc | restricted
      (Barrio et al., 1999)
      third instar larval stage
      larval central nervous system | restricted
      (Barrio et al., 1999)
      Additional Information
      Statement
      Reference

      Embryonic expression is detected in subsets of cells in the PNS where endogenous salm is expressed, as well as in cells in the CNS where endogenous salm and salr are not expressed. Expression is also detected in regions of the epidermis, partially overlapping with the endogenous expression of salm. In the larval CNS and in the wing disc, expression is detected in cells that normally express salm and salr, but additional ectopic expression is also detected.

      (Barrio et al., 1999)
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Ecol\lacZsal.EME
      Name Synonyms
      Secondary FlyBase IDs
        References (2)